{"id":102719,"date":"2026-04-09T23:29:39","date_gmt":"2026-04-10T02:29:39","guid":{"rendered":"https:\/\/ubirataonline.com.br\/stronger-flu-shot-linked-to-nearly-55-lower-alzheimers-risk-study-finds\/"},"modified":"2026-04-09T23:29:39","modified_gmt":"2026-04-10T02:29:39","slug":"stronger-flu-shot-linked-to-nearly-55-lower-alzheimers-risk-study-finds","status":"publish","type":"post","link":"https:\/\/ubirataonline.com.br\/en\/stronger-flu-shot-linked-to-nearly-55-lower-alzheimers-risk-study-finds\/","title":{"rendered":"Stronger Flu Shot Linked to Nearly 55% Lower Alzheimer\u2019s Risk, Study Finds"},"content":{"rendered":"<p><\/p>\n<div>\n<figure id=\"attachment_243242\" aria-describedby=\"caption-attachment-243242\" style=\"width: 777px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/scitechdaily.com\/images\/Vaccine-Science-Chemistry.jpg\"><\/a><figcaption id=\"caption-attachment-243242\" class=\"wp-caption-text\">Researchers investigating influenza vaccination in older adults uncovered evidence that vaccine dosage may play a role in modifying Alzheimer\u2019s disease risk. Credit: Stock<\/figcaption><\/figure>\n<h3>A closer look at vaccine strength revealed a surprising link to brain health.<\/h3>\n<p>A routine visit to a public health office led to an unexpected scientific insight, one that may reshape how researchers think about preventing <span class=\"glossaryLink\" aria-describedby=\"tt\" data-cmtooltip=\"cmtt_44d955d660610a76fe199b3479668107\" data-gt-translate-attributes=\"[{\" attribute=\"\" tabindex=\"0\" role=\"link\">Alzheimer\u2019s<\/span> disease.<\/p>\n<p>A new study from UTHealth Houston reports that older adults who receive a higher dose of the influenza vaccine may have a significantly lower risk of developing Alzheimer\u2019s disease compared to those who receive the standard dose.<\/p>\n<p>The results were published in <em>Neurology<\/em>.<\/p>\n<p>Alzheimer\u2019s disease is the leading cause of dementia, affecting more than 7 million Americans age 65 and older as of 2025. That represents about 1 in 9 people in this age group, and the number is projected to more than double by 2050.<\/p>\n<p><a href=\"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/JAD-220361\">Earlier research from 2022<\/a>, led by Paul Schulz, MD, a professor of neurology at McGovern Medical School at UTHealth Houston and director of the Neurocognitive Disorders Center, found that people age 65 and older had a lower risk of Alzheimer\u2019s disease if they received a flu vaccine.<\/p>\n<p>Now, three years later, Schulz and his team report that the reduction in risk is even greater among those who receive a higher dose of the vaccine.<\/p>\n<h4>A Question That Sparked New Research<\/h4>\n<p>\u201cThe public health department had seen our vaccine research and asked if I could come down to talk to them about it,\u201d said Schulz, who is the senior author of the study and the Rick McCord Professor in Neurology and Umphrey Family Professor in Neurodegenerative Diseases at McGovern Medical School. \u201cWe went through the findings, and they asked if there was a difference with different dosages; I was confused.\u201d<\/p>\n<p>As people reach age 65, the immune system becomes less effective at fighting infections. For this reason, the CDC recommends a high-dose flu vaccine for adults in this age group, which is four times stronger than the standard version given to the general population.<\/p>\n<p>\u201cI was stunned that, as a physician, I didn\u2019t know a higher dose was offered,\u201d Schulz said.<\/p>\n<h4>Vaccine Use and Gaps in Knowledge<\/h4>\n<p>Flu vaccination is recommended for everyone, but influenza can cause more serious complications in people with Alzheimer\u2019s disease.<\/p>\n<p>Before 2022, the CDC did not favor one intramuscular flu vaccine over another for adults age 65 and older. The main recommendation was simply to get vaccinated each year, regardless of the formulation. Previous UTHealth Houston research showed that inactivated flu vaccines were linked to a 40% lower risk of Alzheimer\u2019s disease, but no studies had examined whether higher doses could provide additional protection.<\/p>\n<p>Schulz also noted that the aging population has strained the supply of high-dose vaccines in some areas. As a result, some individuals still receive the standard dose.<\/p>\n<h4>Comparing High- and Standard-Dose Vaccines<\/h4>\n<p>\u201cSo we started looking, and sure enough, we were able to put together thousands and thousands of people over the age of 65 who got the high- or low-dose vaccine. They\u2019re more at risk for Alzheimer\u2019s than anybody else, of course, because it\u2019s age-related and we could look at high-dose versus low-dose and see if there was a difference,\u201d Schulz said.<\/p>\n<p>The team analyzed data from nearly 200,000 adults age 65 and older, including both men and women. The results showed that those who received the high-dose influenza vaccine had a lower risk of Alzheimer\u2019s disease than those who received the standard dose. The protective effect was more pronounced in women.<\/p>\n<p>Compared to the standard-dose flu vaccine, which was associated with a 40% reduction in Alzheimer\u2019s risk, the high-dose vaccine was linked to nearly a 55% reduction in risk among adults age 65 and older.<\/p>\n<p>Reference: \u201cRisk of Alzheimer Dementia After High-Dose vs Standard-Dose Influenza Vaccination\u201d by Avram Samuel Bukhbinder, Yaobin Ling, Lauren Jhin, Elizabeth He, Kristofer Harris, Mya Rodriguez, Jenna Thomas, Gabriela Cruz, Kamal Phelps, Yejin Kim, Luyao Chen, Xiaoqian Jiang and Paul E. Schulz, 1 April 2026, <i>Neurology<\/i>.<br \/><a href=\"https:\/\/doi.org\/10.1212\/WNL.0000000000214782\">DOI: 10.1212\/WNL.0000000000214782<\/a><!--TrendMD v2.4.8--><\/p>\n<p><b>Never miss a breakthrough: <a href=\"https:\/\/scitechdaily.com\/newsletter\/\">Join the SciTechDaily newsletter.<\/a><\/b><br \/><b>Follow us on <a href=\"https:\/\/www.google.com\/preferences\/source?q=scitechdaily.com\">Google<\/a> and <a href=\"https:\/\/news.google.com\/publications\/CAAqLAgKIiZDQklTRmdnTWFoSUtFSE5qYVhSbFkyaGtZV2xzZVM1amIyMG9BQVAB?hl=en-US&amp;gl=US&amp;ceid=US%3Aen\">Google News<\/a>.<\/b><\/p>\n<\/p><\/div>\n<p><a href=\"https:\/\/scitechdaily.com\/stronger-flu-shot-linked-to-nearly-55-lower-alzheimers-risk-study-finds\/\">Source link <\/a><br \/>\nSee more https:\/\/theglobaltrack.com\/<\/p>","protected":false},"excerpt":{"rendered":"<p>Researchers investigating influenza vaccination in older adults uncovered evidence that vaccine dosage may play a role in modifying Alzheimer\u2019s disease risk. Credit: Stock A closer look at vaccine strength revealed a surprising link to brain health. A routine visit to a public health office led to an unexpected scientific insight, one that may reshape how [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":102720,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAow2JLhCw:productID":"","_gspb_post_css":"","maa_idioma":"","maa_pais":"","footnotes":""},"categories":[1],"tags":[10717,13024,8684,5757,5759,5372,26343,10716],"class_list":["post-102719","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ubirata","tag-alzheimers","tag-finds","tag-flu","tag-linked","tag-risk","tag-shot","tag-stronger","tag-study"],"blocksy_meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Stronger Flu Shot Linked to Nearly 55% Lower Alzheimer\u2019s Risk, Study Finds - Ubirat\u00e3 Online Not\u00edcias - A realidade ao seu alcance!<\/title>\n<meta name=\"description\" content=\"A closer look at vaccine strength revealed a surprising link to brain health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ubirataonline.com.br\/en\/stronger-flu-shot-linked-to-nearly-55-lower-alzheimers-risk-study-finds\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Stronger Flu Shot Linked to Nearly 55% Lower Alzheimer\u2019s Risk, Study Finds\" \/>\n<meta property=\"og:description\" content=\"A closer look at vaccine strength revealed a surprising link to brain health.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ubirataonline.com.br\/en\/stronger-flu-shot-linked-to-nearly-55-lower-alzheimers-risk-study-finds\/\" \/>\n<meta property=\"og:site_name\" content=\"Ubirat\u00e3 Online Not\u00edcias - 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