{"id":107040,"date":"2026-04-14T12:22:52","date_gmt":"2026-04-14T15:22:52","guid":{"rendered":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/"},"modified":"2026-04-14T12:22:57","modified_gmt":"2026-04-14T15:22:57","slug":"clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity","status":"publish","type":"post","link":"https:\/\/ubirataonline.com.br\/en\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/","title":{"rendered":"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity"},"content":{"rendered":"


\n<\/p>\n

\n

By A.J. Hostetler<\/span><\/span><\/p>\n

A new analysis of a large international clinical trial finds semaglutide, a compound found in weight loss medications Wegovy and Ozempic, reduces major heart events and lowers fatty liver disease risk in adults with both obesity and heart disease.\u00a0<\/p>\n

People with obesity face a higher risk of heart attacks and strokes. Many also have fatty liver disease that can lead to liver scarring. A common liver disease, metabolic dysfunction-associated steatotic liver disease (MASLD), affects about 4 out of 10 adults<\/a> and is closely linked to obesity, type 2 diabetes and high blood pressure.\u00a0<\/p>\n

Researchers at Virginia Commonwealth University and around the world are studying the effects of semaglutide on both heart and liver diseases. VCU hepatologist Arun Sanyal, M.D., and colleagues last year published results<\/a> from the \u201cEffect of Semaglutide in Subjects with Non-cirrhotic Non-alcoholic Steatohepatitis\u201d (ESSENCE<\/a>) clinical trial, demonstrating that it improves fatty liver disease and lowers the risk factors associated with heart disease.\u202f\u00a0<\/p>\n

Arun Sanyal, M.D., is the director of VCU\u2019s Stravitz-Sanyal Institute for Liver Disease and Metabolic Health. (Enterprise Marketing and Communications)<\/span><\/span><\/p>\n

A new analysis of a separate clinical trial, \u201cSemaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity\u201d (SELECT<\/a>), shows that semaglutide indeed lowers cardiac risks in those who also have fatty liver disease, even those who have advanced liver scarring. The results<\/a> were recently published in the journal Nature Medicine; Sebastian M. Meyh\u00f6fer of Novo Nordisk Pharma GmbH, in Germany, is the paper\u2019s corresponding author and Sanyal is a co-author.\u00a0<\/p>\n

\u201cThis is a landmark study, demonstrating unequivocally the benefits of semaglutide in those at high risk for cardiovascular disease,\u201d said Sanyal, director of VCU\u2019s Stravitz-Sanyal Institute for Liver Disease and Metabolic Health<\/a>.\u00a0<\/p>\n

In this clinical trial, people who injected semaglutide for two years had fewer major heart events, such as heart-related death, heart attack or stroke, than those who got a placebo. And in people with higher scores on a non-invasive measure for liver scarring, called the FIB-4, semaglutide lowered major heart events by about 26%.\u00a0<\/p>\n

Semaglutide also led to a much larger improvement in the fatty liver index, a blood-based measure of liver fat, of about a 28% greater decrease than placebo.\u00a0<\/p>\n

\u201cIn this analysis, we show that these benefits are also seen in those with non-invasive markers for MASLD and liver scarring, including advanced fibrosis. These, together with the data from ESSENCE, provide a strong rational to consider semaglutide in those with MASLD even with advanced fibrosis for its liver and cardiometabolic benefits,\u201d Sanyal said.\u00a0<\/p>\n

Fatty liver disease occurs when fat builds up in the liver, leading to inflammation and scarring. Over time, it can lead to cirrhosis and even liver failure that requires a liver transplant as well as heart disease, making it a major public health concern.\u00a0<\/p>\n

Semaglutide, manufactured by Novo Nordisk, belongs to a class of drugs called GLP-1 receptor agonists. As Wegovy and Ozempic, it is approved by the U.S. Food and Drug Administration for different conditions, including diabetes and obesity. Only Wegovy is FDA-approved<\/a> to reduce cardiovascular disease risks for patients with certain medical conditions. Sanyal, a leading researcher of semaglutide in liver patients, consults for and has received grants from Novo Nordisk.\u00a0<\/p>\n

The SELECT<\/a> clinical trial was an international study conducted at 804 clinical sites across 41 countries, involving over 17,000 patients.\u00a0<\/p>\n

From international clinical trials to high-quality patient care, discover how VCU\u2019s Stravitz-Sanyal Institute for Liver<\/span> Disease and Metabolic Health is making an impact in Virginia and beyond.<\/a><\/span><\/p>\n

Stay informed, stay healthy.<\/span> Sign up for VCU Health\u2019s e-mail newsletter.<\/a><\/span><\/p>\n

\u00a0<\/p>\n<\/p><\/div>\n


\n
Source link <\/a><\/p>","protected":false},"excerpt":{"rendered":"

By A.J. Hostetler A new analysis of a large international clinical trial finds semaglutide, a compound found in weight loss medications Wegovy and Ozempic, reduces major heart events and lowers fatty liver disease risk in adults with both obesity and heart disease.\u00a0 People with obesity face a higher risk of heart attacks and strokes. Many […]<\/p>\n","protected":false},"author":1,"featured_media":107041,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_gspb_post_css":"","maa_idioma":"","maa_pais":"","footnotes":""},"categories":[1],"tags":[28183,28185,7753,5760,28184,7902,26061,10956,11512,4090,5759,1654,5369,10070],"class_list":["post-107040","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ubirata","tag-clinical","tag-diseases","tag-drug","tag-heart","tag-liver","tag-loss","tag-obesity","tag-people","tag-reduces","tag-results","tag-risk","tag-show","tag-trial","tag-weight"],"blocksy_meta":[],"yoast_head":"\nClinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity - Ubirat\u00e3 Online Not\u00edcias - A realidade ao seu alcance!<\/title>\n<meta name=\"description\" content=\"By A.J. Hostetler A new analysis of a large international clinical trial finds semaglutide, a compound found in weight loss medications Wegovy and\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ubirataonline.com.br\/en\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity\" \/>\n<meta property=\"og:description\" content=\"By A.J. Hostetler A new analysis of a large international clinical trial finds semaglutide, a compound found in weight loss medications Wegovy and\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ubirataonline.com.br\/en\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/\" \/>\n<meta property=\"og:site_name\" content=\"Ubirat\u00e3 Online Not\u00edcias - A realidade ao seu alcance!\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/portalubirataonline\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/portalubirataonline\" \/>\n<meta property=\"article:published_time\" content=\"2026-04-14T15:22:52+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-14T15:22:57+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ubirataonline.com.br\/wp-content\/uploads\/2026\/04\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"750\" \/>\n\t<meta property=\"og:image:height\" content=\"504\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"REDA\u00c7\u00c3O: UBIRAT\u00c3 ONLINE - F\u00c1BIO AUGUSTO CELESTINO\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@x.com\/ubirataonline\" \/>\n<meta name=\"twitter:site\" content=\"@ubirataonline\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"REDA\u00c7\u00c3O: UBIRAT\u00c3 ONLINE - F\u00c1BIO AUGUSTO CELESTINO\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/\"},\"author\":{\"name\":\"REDA\u00c7\u00c3O: UBIRAT\u00c3 ONLINE - F\u00c1BIO AUGUSTO CELESTINO\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/#\\\/schema\\\/person\\\/372f87bbd3fdd79b8556b84c98d0bc1c\"},\"headline\":\"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity\",\"datePublished\":\"2026-04-14T15:22:52+00:00\",\"dateModified\":\"2026-04-14T15:22:57+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/\"},\"wordCount\":613,\"publisher\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ubirataonline.com.br\\\/wp-content\\\/uploads\\\/2026\\\/04\\\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg\",\"keywords\":[\"Clinical\",\"diseases\",\"drug\",\"heart\",\"liver\",\"loss\",\"obesity\",\"people\",\"reduces\",\"results\",\"risk\",\"Show\",\"trial\",\"Weight\"],\"articleSection\":[\"Ubirat\u00e3\"],\"inLanguage\":\"en-US\",\"copyrightYear\":\"2026\",\"copyrightHolder\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/en\\\/#organization\"}},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/\",\"url\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/\",\"name\":\"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity - Ubirat\u00e3 Online Not\u00edcias - A realidade ao seu alcance!\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ubirataonline.com.br\\\/wp-content\\\/uploads\\\/2026\\\/04\\\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg\",\"datePublished\":\"2026-04-14T15:22:52+00:00\",\"dateModified\":\"2026-04-14T15:22:57+00:00\",\"description\":\"By A.J. Hostetler A new analysis of a large international clinical trial finds semaglutide, a compound found in weight loss medications Wegovy and\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#primaryimage\",\"url\":\"https:\\\/\\\/ubirataonline.com.br\\\/wp-content\\\/uploads\\\/2026\\\/04\\\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg\",\"contentUrl\":\"https:\\\/\\\/ubirataonline.com.br\\\/wp-content\\\/uploads\\\/2026\\\/04\\\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg\",\"width\":750,\"height\":504,\"caption\":\"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"In\u00edcio\",\"item\":\"https:\\\/\\\/ubirataonline.com.br\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/#website\",\"url\":\"https:\\\/\\\/ubirataonline.com.br\\\/\",\"name\":\"Ubirat\u00e3 Online Not\u00edcias\",\"description\":\"Not\u00edcias de Ubirat\u00e3, regi\u00e3o, Brasil e mundo, com informa\u00e7\u00e3o atualizada e compromisso com o leitor.\",\"publisher\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/#organization\"},\"alternateName\":\"Ubirat\u00e3 Online\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ubirataonline.com.br\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":[\"Organization\",\"Place\"],\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/#organization\",\"name\":\"Ubirat\u00e3 Online Not\u00edcias\",\"alternateName\":\"Ubirat\u00e3 Online\",\"url\":\"https:\\\/\\\/ubirataonline.com.br\\\/\",\"logo\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#local-main-organization-logo\"},\"image\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#local-main-organization-logo\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/portalubirataonline\",\"https:\\\/\\\/x.com\\\/ubirataonline\",\"https:\\\/\\\/mastodon.social\\\/@ubirataonline\",\"https:\\\/\\\/www.facebook.com\\\/groups\\\/311144672285604\",\"https:\\\/\\\/www.facebook.com\\\/UBTAOnline\",\"https:\\\/\\\/www.instagram.com\\\/portalubirataonline\\\/\",\"https:\\\/\\\/twitter.com\\\/ubirataonline\"],\"description\":\"Somos um portal de not\u00edcias independente, criado em 5 de janeiro de 2009, com o objetivo de informar, conectar e valorizar a nossa comunidade de Ubirat\u00e3 e toda aregi\u00e3o. Com conte\u00fado atualizado, confi\u00e1vel e relevante, o Ubirat\u00e3 Online \u00e9 o seu espa\u00e7o para ficar por dentro dos principais acontecimentos locais, regionais, Brasil, Mundo e de interesse geral. Nosso compromisso \u00e9 com a verdade, a transpar\u00eancia e o respeito ao leitor.\",\"legalName\":\"UBIRATA ONLINE NOT\u00cdCIAS\",\"foundingDate\":\"2009-01-05\",\"numberOfEmployees\":{\"@type\":\"QuantitativeValue\",\"minValue\":\"1\",\"maxValue\":\"10\"},\"publishingPrinciples\":\"https:\\\/\\\/ubirataonline.com.br\\\/faq\\\/\",\"address\":{\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#local-main-place-address\"},\"geo\":{\"@type\":\"GeoCoordinates\",\"latitude\":\"-24.5361401\",\"longitude\":\"-52.9921776\"},\"telephone\":[\"+5544998308235\"],\"contactPoint\":{\"@type\":\"ContactPoint\",\"email\":\"contato@ubirataonline.com.br\"},\"openingHoursSpecification\":{\"@type\":\"OpeningHoursSpecification\",\"dayOfWeek\":[\"Monday\",\"Tuesday\",\"Wednesday\",\"Thursday\",\"Friday\",\"Saturday\",\"Sunday\"],\"opens\":\"00:00\",\"closes\":\"23:59\"},\"email\":\"contato@ubirataonline.com.br\",\"vatID\":\"47.621.418\\\/0001-80\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/#\\\/schema\\\/person\\\/372f87bbd3fdd79b8556b84c98d0bc1c\",\"name\":\"REDA\u00c7\u00c3O: UBIRAT\u00c3 ONLINE - F\u00c1BIO AUGUSTO CELESTINO\",\"pronouns\":\"Ele\",\"description\":\"Desde 2003 trabalhando com not\u00edcias.\",\"sameAs\":[\"http:\\\/\\\/ubirataoline.com.br\",\"https:\\\/\\\/www.facebook.com\\\/portalubirataonline\",\"https:\\\/\\\/www.instagram.com\\\/ubirataonline_oficial\",\"https:\\\/\\\/x.com\\\/x.com\\\/ubirataonline\"],\"honorificPrefix\":\"Mr.\",\"honorificSuffix\":\"MD\",\"birthDate\":\"1980-06-16\",\"gender\":\"masculino\",\"award\":[\"V\u00e1rios pr\u00eamios de melhor portal da cidade\"],\"jobTitle\":\"Diretor\",\"url\":\"https:\\\/\\\/ubirataonline.com.br\\\/en\\\/author\\\/ubirataonline\\\/\"},{\"@type\":\"PostalAddress\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#local-main-place-address\",\"streetAddress\":\"Rua dos Coqueiros, 104 - Bairro Boa Vista, Rua dos Coqueiros, 104 Bairro Boa Vista\",\"addressLocality\":\"UBIRATA\",\"postalCode\":\"85440-000\",\"addressRegion\":\"PR\",\"addressCountry\":\"BR\"},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/ubirataonline.com.br\\\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\\\/#local-main-organization-logo\",\"url\":\"https:\\\/\\\/ubirataonline.com.br\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/logoubirataonline-1.webp\",\"contentUrl\":\"https:\\\/\\\/ubirataonline.com.br\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/logoubirataonline-1.webp\",\"width\":500,\"height\":500,\"caption\":\"Ubirat\u00e3 Online Not\u00edcias\"}]}<\/script>\n<meta name=\"geo.placename\" content=\"UBIRATA\" \/>\n<meta name=\"geo.position\" content=\"-24.5361401;-52.9921776\" \/>\n<meta name=\"geo.region\" content=\"Brazil\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity - Ubirat\u00e3 Online Not\u00edcias - A realidade ao seu alcance!","description":"By A.J. Hostetler A new analysis of a large international clinical trial finds semaglutide, a compound found in weight loss medications Wegovy and","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ubirataonline.com.br\/en\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/","og_locale":"en_US","og_type":"article","og_title":"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity","og_description":"By A.J. Hostetler A new analysis of a large international clinical trial finds semaglutide, a compound found in weight loss medications Wegovy and","og_url":"https:\/\/ubirataonline.com.br\/en\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/","og_site_name":"Ubirat\u00e3 Online Not\u00edcias - A realidade ao seu alcance!","article_publisher":"https:\/\/www.facebook.com\/portalubirataonline","article_author":"https:\/\/www.facebook.com\/portalubirataonline","article_published_time":"2026-04-14T15:22:52+00:00","article_modified_time":"2026-04-14T15:22:57+00:00","og_image":[{"width":750,"height":504,"url":"https:\/\/ubirataonline.com.br\/wp-content\/uploads\/2026\/04\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg","type":"image\/jpeg"}],"author":"REDA\u00c7\u00c3O: UBIRAT\u00c3 ONLINE - F\u00c1BIO AUGUSTO CELESTINO","twitter_card":"summary_large_image","twitter_creator":"@x.com\/ubirataonline","twitter_site":"@ubirataonline","twitter_misc":{"Written by":"REDA\u00c7\u00c3O: UBIRAT\u00c3 ONLINE - F\u00c1BIO AUGUSTO CELESTINO","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"NewsArticle","@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#article","isPartOf":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/"},"author":{"name":"REDA\u00c7\u00c3O: UBIRAT\u00c3 ONLINE - F\u00c1BIO AUGUSTO CELESTINO","@id":"https:\/\/ubirataonline.com.br\/#\/schema\/person\/372f87bbd3fdd79b8556b84c98d0bc1c"},"headline":"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity","datePublished":"2026-04-14T15:22:52+00:00","dateModified":"2026-04-14T15:22:57+00:00","mainEntityOfPage":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/"},"wordCount":613,"publisher":{"@id":"https:\/\/ubirataonline.com.br\/#organization"},"image":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#primaryimage"},"thumbnailUrl":"https:\/\/ubirataonline.com.br\/wp-content\/uploads\/2026\/04\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg","keywords":["Clinical","diseases","drug","heart","liver","loss","obesity","people","reduces","results","risk","Show","trial","Weight"],"articleSection":["Ubirat\u00e3"],"inLanguage":"en-US","copyrightYear":"2026","copyrightHolder":{"@id":"https:\/\/ubirataonline.com.br\/en\/#organization"}},{"@type":"WebPage","@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/","url":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/","name":"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity - Ubirat\u00e3 Online Not\u00edcias - A realidade ao seu alcance!","isPartOf":{"@id":"https:\/\/ubirataonline.com.br\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#primaryimage"},"image":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#primaryimage"},"thumbnailUrl":"https:\/\/ubirataonline.com.br\/wp-content\/uploads\/2026\/04\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg","datePublished":"2026-04-14T15:22:52+00:00","dateModified":"2026-04-14T15:22:57+00:00","description":"By A.J. Hostetler A new analysis of a large international clinical trial finds semaglutide, a compound found in weight loss medications Wegovy and","breadcrumb":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#primaryimage","url":"https:\/\/ubirataonline.com.br\/wp-content\/uploads\/2026\/04\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg","contentUrl":"https:\/\/ubirataonline.com.br\/wp-content\/uploads\/2026\/04\/Clinical-trial-results-show-weight-loss-drug-reduces-the-risk.jpeg","width":750,"height":504,"caption":"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity"},{"@type":"BreadcrumbList","@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"In\u00edcio","item":"https:\/\/ubirataonline.com.br\/"},{"@type":"ListItem","position":2,"name":"Clinical trial results show weight loss drug reduces the risk of heart and liver diseases in people with obesity"}]},{"@type":"WebSite","@id":"https:\/\/ubirataonline.com.br\/#website","url":"https:\/\/ubirataonline.com.br\/","name":"Ubirat\u00e3 Online Not\u00edcias","description":"Not\u00edcias de Ubirat\u00e3, regi\u00e3o, Brasil e mundo, com informa\u00e7\u00e3o atualizada e compromisso com o leitor.","publisher":{"@id":"https:\/\/ubirataonline.com.br\/#organization"},"alternateName":"Ubirat\u00e3 Online","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ubirataonline.com.br\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":["Organization","Place"],"@id":"https:\/\/ubirataonline.com.br\/#organization","name":"Ubirat\u00e3 Online Not\u00edcias","alternateName":"Ubirat\u00e3 Online","url":"https:\/\/ubirataonline.com.br\/","logo":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#local-main-organization-logo"},"image":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#local-main-organization-logo"},"sameAs":["https:\/\/www.facebook.com\/portalubirataonline","https:\/\/x.com\/ubirataonline","https:\/\/mastodon.social\/@ubirataonline","https:\/\/www.facebook.com\/groups\/311144672285604","https:\/\/www.facebook.com\/UBTAOnline","https:\/\/www.instagram.com\/portalubirataonline\/","https:\/\/twitter.com\/ubirataonline"],"description":"Somos um portal de not\u00edcias independente, criado em 5 de janeiro de 2009, com o objetivo de informar, conectar e valorizar a nossa comunidade de Ubirat\u00e3 e toda aregi\u00e3o. Com conte\u00fado atualizado, confi\u00e1vel e relevante, o Ubirat\u00e3 Online \u00e9 o seu espa\u00e7o para ficar por dentro dos principais acontecimentos locais, regionais, Brasil, Mundo e de interesse geral. Nosso compromisso \u00e9 com a verdade, a transpar\u00eancia e o respeito ao leitor.","legalName":"UBIRATA ONLINE NOT\u00cdCIAS","foundingDate":"2009-01-05","numberOfEmployees":{"@type":"QuantitativeValue","minValue":"1","maxValue":"10"},"publishingPrinciples":"https:\/\/ubirataonline.com.br\/faq\/","address":{"@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#local-main-place-address"},"geo":{"@type":"GeoCoordinates","latitude":"-24.5361401","longitude":"-52.9921776"},"telephone":["+5544998308235"],"contactPoint":{"@type":"ContactPoint","email":"contato@ubirataonline.com.br"},"openingHoursSpecification":{"@type":"OpeningHoursSpecification","dayOfWeek":["Monday","Tuesday","Wednesday","Thursday","Friday","Saturday","Sunday"],"opens":"00:00","closes":"23:59"},"email":"contato@ubirataonline.com.br","vatID":"47.621.418\/0001-80"},{"@type":"Person","@id":"https:\/\/ubirataonline.com.br\/#\/schema\/person\/372f87bbd3fdd79b8556b84c98d0bc1c","name":"REDA\u00c7\u00c3O: UBIRAT\u00c3 ONLINE - F\u00c1BIO AUGUSTO CELESTINO","pronouns":"Ele","description":"Desde 2003 trabalhando com not\u00edcias.","sameAs":["http:\/\/ubirataoline.com.br","https:\/\/www.facebook.com\/portalubirataonline","https:\/\/www.instagram.com\/ubirataonline_oficial","https:\/\/x.com\/x.com\/ubirataonline"],"honorificPrefix":"Mr.","honorificSuffix":"MD","birthDate":"1980-06-16","gender":"masculino","award":["V\u00e1rios pr\u00eamios de melhor portal da cidade"],"jobTitle":"Diretor","url":"https:\/\/ubirataonline.com.br\/en\/author\/ubirataonline\/"},{"@type":"PostalAddress","@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#local-main-place-address","streetAddress":"Rua dos Coqueiros, 104 - Bairro Boa Vista, Rua dos Coqueiros, 104 Bairro Boa Vista","addressLocality":"UBIRATA","postalCode":"85440-000","addressRegion":"PR","addressCountry":"BR"},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/ubirataonline.com.br\/clinical-trial-results-show-weight-loss-drug-reduces-the-risk-of-heart-and-liver-diseases-in-people-with-obesity\/#local-main-organization-logo","url":"https:\/\/ubirataonline.com.br\/wp-content\/uploads\/2026\/06\/logoubirataonline-1.webp","contentUrl":"https:\/\/ubirataonline.com.br\/wp-content\/uploads\/2026\/06\/logoubirataonline-1.webp","width":500,"height":500,"caption":"Ubirat\u00e3 Online Not\u00edcias"}]},"geo.placename":"UBIRATA","geo.position":{"lat":"-24.5361401","long":"-52.9921776"},"geo.region":"Brazil"},"_links":{"self":[{"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/posts\/107040","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/comments?post=107040"}],"version-history":[{"count":0,"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/posts\/107040\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/media\/107041"}],"wp:attachment":[{"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/media?parent=107040"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/categories?post=107040"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ubirataonline.com.br\/en\/wp-json\/wp\/v2\/tags?post=107040"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}