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The New York Mets<\/a> travel to Wrigley Field on Friday afternoon to start a three-game series against the Chicago Cubs<\/a>. The Mets have lost eight straight games and were swept by the Dodgers and the Athletics in their previous series. The Cubs took two of three games in their most recent series against the Phillies. The Mets (7-12), who have lost three straight on the road, are 4-6 on the road this season. The Cubs (9-9), who have three of their last four, are 4-5 on their home field. Kodai Senga (0-2, 7.07 ERA) is on the hill for New York, while Edward Cabrera (1-0, 1.62 ERA) is starting for Chicago.<\/p>\n First pitch from Wrigley Field in Chicago is set for 2:20 p.m. ET. Chicago is a -157 favorite on the money line (risk $157 to win $100) in the latest Mets vs. Cubs odds, while the over\/under, is 10.5. Before making any Cubs vs. Mets picks, be sure to see the Mets vs. Cubs predictions and betting advice from SportsLine’s proven computer model<\/a>.\u00a0<\/p>\n Visit our\u00a0DraftKings promo code<\/a><\/span>\u00a0review to see their latest offers and get started.<\/strong><\/p>\n The SportsLine Projection Model simulates every MLB game 10,000 times. It was a profitable 35-29 on top-rated MLB money-line picks last season. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following its\u00a0MLB betting<\/a>\u00a0picks at\u00a0sportsbooks<\/a>\u00a0and on\u00a0betting sites<\/a>\u00a0could have seen strong returns.\u00a0 \u00a0\u00a0<\/p>\n Now, the model has set its sights on Mets vs. Cubs<\/a> and just locked in its picks and MLB predictions.\u00a0You can head to SportsLine now to see the model’s picks<\/a>. Here are several\u00a0MLB odds<\/a>\u00a0and betting lines for Mets vs. Cubs:<\/p>\n